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Kodama H, Yamaguchi R, Fukuda J, Kasai H, Tanaka T

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The headline mechanisms: Angiogenesis via VEGFR2/Akt/eNOS: This is clinically significant because tendons and ligaments are notoriously hypovascular

Even with treatment, it may take months for the pigmentation to clear up

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607 Clausenamide, an alkaloid isolated from Clausena lansium , interacts directly with Ser663 of ALOX5, blocking the nuclear translocation of ALOX5, alleviating lipid peroxide accumulation and ferroptosis in dopaminergic neurons, significantly improving behavioral deficits in PD mouse models, and providing an attractive strategy for PD treatment